http://hdl.handle.net/10884/1225 Mon, 27 Apr 2026 17:14:40 GMT 2026-04-27T17:14:40Z http://hdl.handle.net/10884/1685 Title: What influences interruption of continuous renal replacement therapy in intensive care unit patients: Authors: Xiaomei, Xia; Yuliang, Chong; Jianhong, Qiao; Moreira, Paulo; Xiujuan, Xue Abstract: Background: Evidence suggests that 8%–10% of ICU patients receive renal replacement therapy. However, there is a high rate of unplanned CRRT interruption, ranging between 17% and 74%. Studies on unplanned interruption of CRRT mainly focused on the retrospective investigation of related risk factors and conclusions have been diverse. Aims: This article aims to clarify the main influencing factors related to unplanned interruption of continuous renal replacement therapy (CRRT) in adult patients in intensive care units (ICUs). Study Design: A literature review and meta-analysis were undertaken. Following the application of the Newcastle–Ottawa Scale (NOS), a total of 15 articles were included in a total of 2132 patients who underwent 3690 CRRT procedures and 2181 unplanned interruption times. The methodological guideline of a scoping review was applied for the evidence synthesis while applying the meta-analysis quantitative methodological guideline to identify and clarify main influencing factors related to unplanned interruption of CRRT. The reporting Prisma Protocol was followed. Results: Longer filter life and prothrombin activation time, higher red blood cell count, greater transmembrane pressure, faster blood flow rate, intermittent saline irrigation, lower creatinine level, low prothrombin activity and pre-dilution are factors identified to potentially affect unplanned CRRT in ICU patients. Conclusions: Available evidence suggests four clinical challenges associated with unplanned CRRT interruption, namely: (a) effects of red blood cell count, filter life, cross-mode pressure, blood flow velocity, prothrombin activity and activated partial thrombin time on unplanned interruption; (b) influence of dilution mode on unplanned interruption; (c) influence of intermittent saline irrigation on unplanned interruption; (d) influence of Scr level on unplanned interruption. Relevance to Clinical Practice: The potential to increase the ability to better manage unplanned CRRT in ICUs has been identified in this article and constitutes a relevant potential health care management contribution that can be implemented by nurses. Sun, 15 Sep 2024 00:00:00 GMT http://hdl.handle.net/10884/1685 2024-09-15T00:00:00Z http://hdl.handle.net/10884/1683 Title: Insights into uncovered public health risks. The case of asthma attacks among archival workers: Authors: Yang, Liu; Xinting, Chen; Aie, Zhang; Ruiqi, Xu; Moreira, Paulo; Mei, Dou Abstract: Objective: To ascertain the prevalence of asthma attacks among archivists and identify the associated occupational factors in this understudied professional population. Methods: We conducted a cross-sectional, questionnaire-based study among 1,002 archival workers. A multiple logistic regression was conducted to identify the association between asthma attacks and occupational exposures. The Strobe Protocol was applied. Results: 999 workers were included in the final analysis with the asthma prevalence of 33.3%. Main factors associated with asthma attacks (OR [95% CI]) were the presence of chemically irritating odors (2.152 [1.532–3.024]), mold odors (1.747 [1.148–2.658]), and insects (1.409[1.041–1.907]). A significant synergistic effect was observed between chemical irritants and mold, the odds ratio was 7.098 (95% CI, 4.752–10.603). Conclusion: There was a high prevalence of asthma attacks among archival workers, an under-studied population. Chemical irritants, molds and insects were associated with their asthma attacks. Notably, this study’s data analysis has revealed a strong synergy (OR = 7.098) between chemical odors and molds in the workplace. While the existing international literature on this specific interaction remains somewhat limited, previous studies have already demonstrated the potential for chemical irritants, such as sulfur dioxide and ozone, to synergistically interact with inhalable allergens, including fungi, molds and dust mites. Consequently, this interaction seems to exacerbate asthma symptoms and perpetuate untreated exposure. Furthermore, in damp and damaged buildings, the presence of microbial components, such as cellular debris or spores released during fungal growth can trigger an inflammatory response, potentially served as a shared pathway for the development of asthma among individuals exposed to these hazardous factors. Wed, 21 Aug 2024 00:00:00 GMT http://hdl.handle.net/10884/1683 2024-08-21T00:00:00Z http://hdl.handle.net/10884/1681 Title: Mobile apps for cancer patients: Identifying positive impacts and concerns Authors: Leidong, Wei; Monachino, Michelle; Lloyd-Williams, Don; Nguyen, Thi Le Ha; Dsouza, Brayal; Paulo, Moreira Abstract: Background: Mobile health is being increasingly considered as a strategy to deliver healthcare to people with chronic diseases. This stands particularly true for cancer management where treatment is being progressively administered at home, requiring more involvement, education, and changes in behavior from patients. This article aims to identify the main axes of intervention for behavioral change of mHealth in cancer management and its relative impacts, as well as identify recent evidence on user preferences for optimal engagement in mHealth-based behavioral change strategies. Methodological Approach: A literature search was carried out in the Databases PubMed and Cochrane during the period October–December 2023. The search retrieved 505 initial entries narrowed down to 21 articles included in this commentary. Results: Evidence is available on Mobile apps for cancer management being used to successfully promote behavioral changes in the areas of treatment adherence, symptoms self-management, communication with healthcare professionals, and holistic well-being in cancer patients. These are activities traditionally relevant in healthcare management interventions and contribute to further developing the relevance of the field of Digital Health in healthcare management. Relevance to Clinical Practice: The article contributes to a practical understanding of how Mobile interventions are being applied to promote higher self-care, a better emotional status, lesser adverse impacts, and, ultimately, increased survival rates for cancer patients. Several cancer patients’ preferences were identified for the promotion of user engagement related to app design, available features, interoperability, and app creation process, as well as advanced healthcare management intervention. Preferences were found to be different for adolescents and young adult cancer patients when compared to other cohort groups. Thu, 21 Nov 2024 00:00:00 GMT http://hdl.handle.net/10884/1681 2024-11-21T00:00:00Z http://hdl.handle.net/10884/1670 Title: Adaptation of the Work-Related Quality of Life-2 Scale (WRQoL-2) among Portuguese Workers Authors: Sabino, Ana; Moreira, Ana; Cesário, Francisco; Coelho, Mafalda Pinto Abstract: In the present study we aimed to fulfill two main goals. The first was to adapt the WRQoL-2 Scale among Portuguese workers and the second was to verify the associations between WRQoL-2 dimensions and perceived organizational performance dimensions (e.g., social and economic). To reach our research goals, we used a sample of 635 Portuguese workers. The WRQoL Scale has been widely used for academic and practical ends and comprises six dimensions: Job and Career Satisfaction, Control atWork, GeneralWell-Being, Home–Work Interface, Stress atWork, andWorking Conditions. Recently, the authors proposed a revised measure—WRQoL-2—in which they added a seventh dimension—Employee Engagement. As this second version had not yet been translated into the Portuguese language for Portugal, this was our first goal. By performing a set of statistical analyses such as EFA, CFA, reliability, convergent and discriminant validity, and invariant analysis, the results suggested a six-factor structure where the dimensions of Job and Career Satisfaction and Employee Engagement were united. The final structure suggested good reliability as well as convergent and discriminant validity as it showcased invariance according to gender and sector. Because there is a lack of studies focusing on the links between quality of work life and organizational performance, we then tested the interplay between WRQoL-2 and perceived organizational performance dimensions, and we verified that, although most are significantly associated, the results suggest a low intensity. This work also presents several theoretical and practical implications. Mon, 01 Jul 2024 00:00:00 GMT http://hdl.handle.net/10884/1670 2024-07-01T00:00:00Z